In this article, recommendations for mobile, digital health application (mHealth) development are given based on a literature scan and review on barriers older adults encounter when using mHealth applications. Physical, motivational, cognitive and perceptual age-related declines should influence the design choices. The user interface should include age-appropriate visual, motor and cognitive features. Persuasive design strategies, self-monitoring and behavior change techniques, including feedback and self-regulation, should be implemented to facilitate behavior and attitude change and adherence. Data security needs to be ensured. A participatory process and co-creation is essential to meet the needs of older adults.